Tess Eidem, Ph.D.
As a kid, what drew me to science was pretty ordinary stuff. I asked simple questions like, “Where are those ants going and what are they doing?” and “What are the stars made of and why do they move in the sky?” The more questions I was able to answer, the more follow-up questions I had, and there was always more to learn. In college, I started learning by exploring in the laboratory and asking questions no one had answers to. I found that I loved pushing the boundaries of human understanding, and I wanted to push more—so I went to graduate school to become a trained scientist.
As a graduate researcher, I worked to find innovative ways to kill “bad” bacteria like Staphylococcus aureus, discovering new antibiotic molecules and fighting antibiotic resistance. I continued to conduct research as a postdoctoral fellow and started branching into science communication and teaching to feed my creative side. I left the bench to gain additional training in project management and started a fermented food business with my husband to help others grow their own healthy microbiomes. I am thrilled to be at Paul Smith’s College to connect my experiences as a microbiologist, communicator, leader, and entrepreneur to prepare students with the skills and knowledge to combat 21st-century challenges to human health and the environment.
Interests and Activities
Although we can’t see microbes and molecules, they are all around us and essential for life on Earth. I am fascinated with how these tiny things make a big impact on human health and the environment, and I continue to explore how we can utilize these tiny guys to protect and improve our world.
Microbes are also a pretty big deal when it comes to food—from beer to sauerkraut to cheese, they bring the unique flavors and “friendly” bacteria we want in our gut. Experimenting in the kitchen is a fun pastime for my family—the best experiments are those you can eat!
Although I love science, I like to exercise other parts of my brain too. I love singing, playing guitar, and writing music. Spending time in the great outdoors and practicing yoga are ways that find my center, and I’m happiest with many friends and puppies around.
BIO 102 Biology II
BIO 376 Environmental Microbiology
2014-2018 | University of Colorado Boulder | Researcher & Associate Director of Education for STROBE Science and Technology Center
2007-2013 | University of Nebraska Medical Center and University of Rochester| Ph.D. in Pathology and Microbiology
2003-2007 | University of Nebraska at Omaha | B.S. in Biology, Minor in Chemistry
Visit my website to see what I’m up to: tessthescientist.com
Liang H, Zhou G, Ge Y, D’Ambrosio EA, Eidem TM, Blanchard C, Shehatou C, Chatare VK, Dunman PM, Valentine AM, Voelz VA, Grimes CL, Andrade RB. (2018) Elucidating the inhibition of peptidoglycan biosynthesis in Staphylococcus aureus by albocycline, a macrolactone isolated from Streptomyces maizeus. Bioorg Med Chem Lett., 26(12):3453-3460.
Lounsbury N, Eidem T, Colquhoun J, Mateo G, Abou-Gharbia M, Dunman PM, Childers WE. (2018) Novel inhibitors of Staphylococcus aureus RnpA that synergize with mupirocin. Bioorg Med Chem Lett. 28(6):1127-31.
Eidem TM, Kugel JF, Goodrich JA. (2016) Noncoding RNAs: Regulators of the Mammalian Transcription Machinery. J Mol Biol, 428(12):2652-9.
Abrisch RG, Eidem TM, Yakovchuk P, Kugel JF, Goodrich JA. (2015) Infection by Herpes Simplex Virus Type-1 causes near-complete loss of RNA polymerase II occupancy on the host cell genome. J Viro, 90(5):2503-13.
Eidem TM, Lounsbury N, Emery JF, Bulger J, Smith A, Abou-Gharbia M, Childers W, Dunman PM. (2015) Small molecule inhibitors of Staphylococcus aureus RnpA-mediated RNA turnover and tRNA processing. Antimicrob Agents and Chemother, 59(4):2016-28.
Tomaras AP, McPherson CJ, Kuhn M, Carifa A, Mullins L, George D, Desbonnet C, Eidem TM, Montgomery JI, Brown MF, Reilly U, Miller AA, O’Donnell JP. (2014) Novel LpxC inhibitors as new antibacterial agents and tools to study the regulation of lipid A biosynthesis in Gram-negative pathogens. mBio, 5(5):e01551-14.
Eidem TM. (2014) Isolation of Staphylococcus sp. RNA. Staphylococcus Epidermidis: Methods and Protocols. Methods in Molecular Biology, 116. Humana Press.
Eidem TM, Coughlan A, Towler MR, Dunman PM, Wren AW. (2014) Drug-eluting cements for hard tissue repair: A comparative study using vancomycin and RNPA1000 to inhibit growth of Staphylococcus aureus. J Biomater Appl, 28(8) 1235-1246.
Price-Whelan A, Poon CK, Benson MA, Eidem T, Roux CM, Boyd J, Dunman PM, Torres VJ, Krulwich TA. (2013) Transcriptional profiling of Staphylococcus aureus during growth in 2 M NaCl leads to clarification of physiological roles for Kdp and Ktr K+ uptake systems. mBio, 4(4):e00407-13.
Annadurai S, Martinez R, Canney DJ, Eidem T, Dunman PM, Abou-Gharbia M. (2012) Design and synthesis of 2-aminothiazole based antimicrobials targeting MRSA. Bioorg Med Chem Lett, 22(24): p. 7719-25.
Eidem TM, Roux CM, Dunman PM. (2012) RNA Decay: a Novel Therapeutic Target in Bacteria. WIRES RNA, 3(3): p. 443-54.
Truong-Bolduc QC, Dunman PM, Eidem T, Hooper DC. (2011) Transcriptional profiling of the global regulator NorG, a GntR-like protein of Staphylococcus aureus. J Bacteriol, 193(22):6207-14.
Ramirez SH, Potula R, Fan S, Eidem T, Papugani A, Reichenbach N, Dykstra H, Weksler BB, Romero IA, Couraud PO, Persidsky Y. (2009) Methamphetamine disrupts blood-brain barrier function by induction of oxidative stress in brain endothelial cells. J Cereb Blood Flow Metab, 29, 1933-45.
Whitney NP, Eidem TM, Peng H, Huang Y, Zheng JC. (2009) Inflammation mediates varying effects in neurogenesis: relevance to the pathogenesis of brain injury and neurodegenerative disorders. J Neurochem, 108, 1343-1359.
Sellin MK, Eidem TM, Kolok, AS. (2007) Cadmium exposures in fathead minnows: are there sex-specific differences in mortality, reproductive success, and Cd accumulation? Arch Environ Contam Toxicol, 52, 535-540.
Tess Eidem, Ph.D.
Natural Science Department